This Tenderizer Machine comprises of activating and tenderizing systems. To activate the meat loaf, the activating system can squeeze and mangle the fiber tissue in the meat loaf. The productivity can be greatly improved, and the cutting surface is rather solid and good-looking. The tenderizing system can deeply-cut into the meat while the original shape is properly maintained. Sufficient saline and additives can be adsorbed by the meat during the course of rolling, kneading and massaging, resulting in a shorter process time, better tissue structure of the meat, and the final product features softness and tenderness.